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June 9, 2017

The Human Genome Project (HGP) was established in 1990 with the aim of sequencing the entire human...

March 13, 2017

This genome assembly approach utilises an existing complete reference genome sequence to assemble newly sequenced genome, by aligning...

March 11, 2017

Following my post on the de novo genome assembly problem, it should be pointed out...

March 9, 2017

De novo assembly is a hierarchical data structure.

Overlapping reads form contiguous sequences (contigs), and contigs form scaffolds. Scaffolds are formed using insert size data from paired-end sequencing and elucidate the order and orientation of contigs.

Ther...

March 7, 2017

Genome assembly is the process of assembling a genomic sequence after DNA sequencing (during which the DNA molecule is cut in to...

May 1, 2016

Here are some really good slides on genome assembly algorithms.

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PhDomics by Fatima